KIs

The voucher can help to pay for the cost of technology-related projects and services at the participating KIs.

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These activities should facilitate the transfer of know-how from the KIs to the SMEs.

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Another advantage, which will be later discussed in the article, is the ability to produce KIs that hit several targets at once.

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The most evident advantage is that KIs can hit targets inside the cell while antibodies can only bind targets presented on the cell surface, so internal targets are approachable only by KIs.

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Exelixis is active in the ever growing market of kinase inhibitors (KIs) for the treatment of cancer, that is, drugs that block the activity of kinases in cancer cells.

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There may also be a commercial value in multi-targeted KIs because one drug can theoretically replace two or three single targeted agents, thereby lowering the cost of treatment.

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Another advantage is the fact that KIs can be given orally, which is a major factor in terms of patient convenience, especially given the typical long treatment duration associated with targeted therapies.

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