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Examples
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Prescription medications to treat wrinkles contain a vitamin A compound called all-trans retinoic acid - often referred to as retin A by physicians, although this is also a trade name of one medication.
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When a light quantum is taken up by the visual pigment the chromophore changes its form: there is an isomerization from II-cis to all-trans.
Nobel Prize in Physiology or Medicine 1967 - Presentation Speech 1968
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Here, we investigate if different methods of cell differentiation and use of all-trans retinoic acid (RA) could be causative factors and how they might impact Xist expression.
BioMed Central - Latest articles Janice Ahn 2010
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They are also given all-trans retinoic acid - vitamin A in its acid form - and about 40 per cent less chemotherapy.
The Globe and Mail - Home RSS feed Lisa Priest 2010
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The FDA has granted Orphan Drug Designation for APL and Fast Track Designation for the treatment of adult patients with relapsed or refractory APL following treatment with all-trans retinoic acid
unknown title 2009
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A total of 102 patients (70 in Brazil, 25 in Mexico, and seven in Uruguay) were enrolled and received treatment identical to the LPA 2005 protocol set forth by the PETHEMA working group of the Spanish Association of Hematology and Hemotherapy, which consisted of all-trans retinoic acid, idarubicin, mitoxantrone, and cytosine arabinoside combination therapy.
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Liu PT, Krutzik SR, Kim J, Modlin RL (2005) Cutting edge: all-trans retinoic acid down-regulates TLR2 expression and function.
PLoS ONE Alerts: New Articles Philip T. Liu et al. 2009
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In developed countries, the standard treatment for acute promyelocytic leukemia (APL), as recommended by evidence-based guidelines such as those of the EuropeanLeukemiaNET, is a combination of all-trans retinoic acid, a derivative of Vitamin A, and an anthracycline-based chemotherapy; this results in a five-year overall survival rate of approximately 90 percent.
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This favorable opinion for tamibarotene in the European Union (EU) is in addition to the Orphan Drug Designation for APL and Fast Track Designation for the treatment of adult patients with relapsed or refractory APL following treatment with all-trans retinoic acid
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The FDA has granted Orphan Drug Designation for APL and Fast Track Designation for the use of tamibarotene in patients with relapsed or refractory APL following treatment with all-trans retinoic acid (ATRA) and arsenic trioxide.
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