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Examples
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[3] An advantage of this regimen is the reduced toxicity from the low dose of colchicine and that the colchicine helps prevent flares if allopurinal is later started.
Citizendium, the Citizens' Compendium - Recent changes [en] 2009
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A Phase III, randomized, double-blind multi-center trial, known as the APEX (Allopurinol - and Placebo-Controlled, Efficacy Study of Febuxostat) trial, was conducted to compare the safety and efficacy of febuxostat with allopurinal and a placebo in patients with high urate levels
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