brain-crazed

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“They are become frantic, man — clean brain-crazed,” answered the king.

The Fortunes of Nigel 2004
There was never a tender glance, a fluttering sigh, a soft smile, a low-toned, thrilling word passed between the false flirt and the fascinated husband, that was not seen and heard by the heart-broken, brain-crazed young wife!

Cruel As The Grave Emma Dorothy Eliza Nevitte Southworth 1859
"They are become frantic, man -- clean brain-crazed," answered the king.

The Fortunes of Nigel Walter Scott 1801