Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun Any of various enzymes that catalyze the addition of a carboxyl group.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry Any enzyme that catalyzes either a carboxylation or decarboxylation reaction

Etymologies

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Examples

  • Deficiencies of pyruvate dehydrogenase (PDH) and pyruvate carboxylase (PDH and PC); Leigh syndrome

    Biochemical Genetics-Metabolic Disease 2010

  • In the initial step of the Calvin Cycle, carbon dioxide (from the atmosphere) reacts with a five-carbon compound, ribulose bisphosphate (RuBP), in a reaction that is catalyzed by the enzyme RuBP carboxylase/oxygenase ( "RuBisco").

    Photosynthesis 2009

  • The physical separation of H - from D-labeled molecules made possible by their different rates of reaction was used to establish that the transfer of hydrogen in G6P isomerase was intramolecular9 and that the site of attachment of CO2 to ribulose-1, 5-P2 to produce two molecules of phosphoglyceric acid had to be to C-2 rather than C-4 in the RUDP carboxylase reaction47.

    Irwin Rose - Autobiography 2005

  • In this path CO2 is converted to phosphoglycerate via the enzyme RuBisCO Ribulose biphosphate carboxylase/oxygenase.

    Potential Academic Misconduct by the Euro Team « Climate Audit 2006

  • Genes encoding plastid acetyl-Co-A carboxylase . . . and the evolutionary history of wheat.

    On Food and Cooking, The Science and Lore of the Kitchen Harold McGee 2004

  • Genes encoding plastid acetyl-Co-A carboxylase . . . and the evolutionary history of wheat.

    On Food and Cooking, The Science and Lore of the Kitchen Harold McGee 2004

  • State and his team found a family with TS with a rare mutation in a gene called 1-histidine de carboxylase (HDC).

    PhysOrg.com - latest science and technology news stories 2010

  • The expression of the enzymes glutamine synthetase and pyruvate carboxylase along with glial glutamate transporters

    PLoS ONE Alerts: New Articles Samir Koirala et al. 2010

  • Pharmacological normalization of lipid abundance in DCs with an inhibitor of acetyl-CoA carboxylase restored the functional activity of DCs and substantially enhanced the effects of cancer vaccines.

    Naturejobs - All Jobs Donna L Herber 2010

  • At the same time, acetyl-CoA carboxylase (an enzyme needed for fatty acid synthesis) was inactivated and there was activation of PPARa (a protein that modulates fat metabolism), acyl-CoA oxidase (an enzyme that plays a role in fatty acid metabolism), and carnitine palmitoyltransferase-1A (an enzyme needed for the breakdown of fatty acids) in the liver.

    Medlogs - Recent stories 2010

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