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Examples
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BCG immunization induced the expansion of CD8+ DC which expressed higher levels of co-stimulatory molecules compared with CD8
PLoS ONE Alerts: New Articles Xiaoling Gao et al. 2010
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Since the function of DC in modulating immune responses is largely dependent on their expression of co-stimulatory molecules and the production of cytokines, we further analyzed the surface markers on the DC subsets by three-color staining (CD11c, CD8 and a particular surface marker).
PLoS ONE Alerts: New Articles Xiaoling Gao et al. 2010
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Specifically, the report entitled, "From transcriptome analysis to therapeutic anti-CD40L treatment in the SOD1 model of amyotrophic lateral sclerosis," details the characterization of the co-stimulatory pathway, which is a key regulator of immune system response, and the development of ALS TDI 00846 as a therapeutic biologic.
Medindia Health News 2010
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The functional difference may be related to their expression of co-stimulatory molecules and cytokine production patterns.
PLoS ONE Alerts: New Articles Xiaoling Gao et al. 2010
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One potential explanation for this difference is that the ability of vhs to antagonize NF-kB-dependent genes (IL-6, TNF-α) may be separate from its ability to block IFN-dependent events (co-stimulatory molecule up-regulation).
PLoS ONE Alerts: New Articles Christopher R. Cotter et al. 2010
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Because we could slow the disease, at least in the mice, when we blocked the co-stimulatory pathway with ALS TDI 00846, we believe that we have implicated an immune process that may drive the degeneration of neurons.
Medindia Health News 2010
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Because we could slow the disease, at least in the mice, when we blocked the co-stimulatory pathway with ALS TDI 00846, we believe that we have implicated an immune process that may drive the degeneration of neurons.
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Fernando Vieira, M.D. Specifically, the report entitled, "From transcriptome analysis to therapeutic anti-CD.0L treatment in the SOD. model of amyotrophic lateral sclerosis," details the characterization of the co-stimulatory pathway, which is a key regulator of immune system response, and the development of ALS TD. 00846 as a therapeutic biologic.
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Because we could slow the disease, at least in the mice, when we blocked the co-stimulatory pathway with
THE MEDICAL NEWS Editors 2010
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Demangel et al found that bone marrow-derived DCs that were infected with BCG showed increased expression/production of MHC class II antigens, co-stimulatory molecules and immune regulatory cytokines.
PLoS ONE Alerts: New Articles Xiaoling Gao et al. 2010
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