Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry Any
enzyme thatcatalyzes adeadenylation reaction
Etymologies
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Examples
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Semotok JL, Cooperstock RL, Pinder BD, Vari HK, Lipshitz HD, et al. (2005) Smaug recruits the CCR4/POP2/NOT deadenylase complex to trigger maternal transcript localization in the early Drosophila embryo.
PLoS ONE Alerts: New Articles Hitomi Suzuki et al. 2010
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Semotok JL, Cooperstock RL, Pinder BD, Vari HK, Lipshitz HD, et al. (2005) Smaug recruits the CCR4/POP2/NOT deadenylase complex to trigger maternal transcript localization in the early Drosophila embryo.
PLoS ONE Alerts: New Articles Hitomi Suzuki et al. 2010
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The resulting structures suggest a molecular deadenylase mechanism involving
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This first structure of a deadenylase belonging to the EEP family adopts a complete
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CCR4, an evolutionarily conserved member of the CCR4-NOT complex, is the main cytoplasmic deadenylase.
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In vitro deadenylase assays confirm the critical active site residues and show that the nuclease domain of CNOT6L exhibits full Mg
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CCR4, crystal structure, deadenylase, et al. & contentID = 10.1038/emboj. 2010.152&publicationDate = 07/13/2010&Vol = & Issue = current "
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