Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective That has undergone
dedifferentiation - verb Simple past tense and past participle of
dedifferentiate .
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- adjective having experienced or undergone dedifferentiation or the loss of specialization in form or function
Etymologies
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Examples
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IF we figure out how to turn adult stem cells – what GW is supporting here – into embryonic stem cells, that is cells that are dedifferentiated to the point that they can recreate any human organ then the Prez is supporting the creation of ARTIFICIAL blstocysts that can be allowed to develop into EMBRYOES.
Think Progress » Bush on Stem Cell Veto: ‘These Boys and Girls Are Not Spare Parts’ 2006
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But in the new research, scientists added genes to mature cells that turned back their cellular clocks, or dedifferentiated them, restoring them to an immature, unprogrammed state.
Skin-Cell to Stem-Cell Hack Is Like 'Turning Lead Into Gold' By Brandon Keim 2007
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But in the new research, scientists added genes to mature cells that turned back their cellular clocks, or dedifferentiated them, restoring them to an immature, unprogrammed state.
Stem Cell Breakthrough Is Like 'Turning Lead Into Gold' Brandon Keim 2007
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At the most extreme dedifferentiated state embryonic stem cells are so dedifferentiated that they have the ability to become all more specialized cell types.
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At the most extreme dedifferentiated state embryonic stem cells are so dedifferentiated that they have the ability to become all more specialized cell types.
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We found no regulation in proliferation data from dedifferentiated or embryonic cells, and we observed a dual control in proliferation data from normal mouse bone marrow cells, and from normal human fibroblasts (however, the latter was a short series).
PLoS ONE Alerts: New Articles Michel Laurent et al. 2010
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In contrast, dedifferentiated liver cells and undifferentiated embryonic cells displayed no coordination at all, consistent with their undetermined fate
PLoS ONE Alerts: New Articles Michel Laurent et al. 2010
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Lefebvre V, Peeters-Joris C, Vaes G. Modulation by interleukin 1 and tumor necrosis factor alpha of production of collagenase, tissue inhibitor of metalloproteinases and collagen types in differentiated and dedifferentiated articular chondrocytes.
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Liposarcoma represents a unique model insofar as some well-differentiated liposarcomas progress to non-lipogenic, so-called 'dedifferentiated,' forms.
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To study the genetic changes in dedifferentiated liposarcomas, paired well-differentiated and dedifferentiated components of 29 tumors were analyzed separately by array-based comparative genomic hybridization.
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