Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry The removal of
phosphate groups from a compound, especially from a biological compound
Etymologies
Sorry, no etymologies found.
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Examples
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But what we stumbled on was another quite unexpected reaction: i.e. that muscle phosphorylase was regulated by phosphorylation-dephosphorylation.
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We therefore expect the development of drugs which make it possible to influence imbalances by supplying inhibitors and activators directed against the phosphorylation/dephosphorylation components.
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Phosphorylation-dephosphorylation cycle of proteins pp. Fredholm, B. Molekylär farmakologi - vägen till selektiv farmakoterapi.
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It further shows how phosphorylation and dephosphorylation intimately interact.
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However, the phosphate groups can also be removed from the protein in a regulated fashion dephosphorylation.
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Thus, AKAP5 can allow for crosstalk between signaling molecules that are co-targeted as well as provide tight control of both phosphorylation and dephosphorylation of substrates present near the scaffold complex
PLoS ONE Alerts: New Articles Michael Weisenhaus et al. 2010
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The phosphorylation and dephosphorylation of CDC2 also play important regulatory roles in cell cycle control.
PLoS ONE Alerts: New Articles Gang Wu et al. 2010
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Extent of dephosphorylation was measured by adding 500 ng of purified Mstp cat to a reaction mixture containing phosphorylated PknJ-KD and mtPykA for increasing time-points.
PLoS ONE Alerts: New Articles Gunjan Arora et al. 2010
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Taken together, our data show that Wip1 has an essential role in dephosphorylation of γ-H2AX to silence the checkpoint and restore chromatin structure once DNA damage is repaired.
Naturejobs - All Jobs L Macůrek 2010
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Sandebring A, Thomas KJ, Beilina A, van der Brug M, Cleland MM, et al. (2009) Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1.
PLoS ONE Alerts: New Articles Angela C. Poole et al. 2010
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