Definitions

from The Century Dictionary.

  • Difficult; hard; arduous; perplexing.
  • Reluctant; scrupulous.

from the GNU version of the Collaborative International Dictionary of English.

  • adjective obsolete Difficult; hard to manage; stubborn.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • adjective obsolete Hard to work with; stubborn.
  • adjective obsolete Difficult.

Etymologies

from Wiktionary, Creative Commons Attribution/Share-Alike License

From late Old French difficile, from Latin difficilis, from dis- + facilis ("easy").

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Examples

  • And there's actually a very specific experiment I'd like you to discuss, if you could, and that had to do with a patient who had a C. difficile, which is a bacterial infection that causes such extreme diarrhea that some elderly people die as a result.

    Bacterial Bonanza: Microbes Keep Us Alive 2010

  • And there's actually a very specific experiment I'd like you to discuss, if you could, and that had to do with a patient who had a C. difficile, which is a bacterial infection that causes such extreme diarrhea that some elderly people die as a result.

    Bacterial Bonanza: Microbes Keep Us Alive 2010

  • And there's actually a very specific experiment I'd like you to discuss, if you could, and that had to do with a patient who had a C. difficile, which is a bacterial infection that causes such extreme diarrhea that some elderly people die as a result.

    Bacterial Bonanza: Microbes Keep Us Alive 2010

  • And there's actually a very specific experiment I'd like you to discuss, if you could, and that had to do with a patient who had a C. difficile, which is a bacterial infection that causes such extreme diarrhea that some elderly people die as a result.

    Bacterial Bonanza: Microbes Keep Us Alive 2010

  • And there's actually a very specific experiment I'd like you to discuss, if you could, and that had to do with a patient who had a C. difficile, which is a bacterial infection that causes such extreme diarrhea that some elderly people die as a result.

    Bacterial Bonanza: Microbes Keep Us Alive 2010

  • And there's actually a very specific experiment I'd like you to discuss, if you could, and that had to do with a patient who had a C. difficile, which is a bacterial infection that causes such extreme diarrhea that some elderly people die as a result.

    Bacterial Bonanza: Microbes Keep Us Alive 2010

  • Clostridium difficile, which is especially lethal to the elderly, suggest it prevents recurrence far better than currently used medications.

    Yahoo! News: Business - Opinion 2011

  • The study examined hospital patients infected with the drug-resistant bacteria Clostridium difficile, which is infamous for causing diarrhea in hospitalized patients and responsible for more deaths in the United States than all other intestinal infections combined.

    Yahoo! News: Business - Opinion 2011

  • Food and Drug Administration next week for a clearance to market its Illumigene molecular test for C. difficile, which is currently undergoing a clinical trial.

    Los Angeles Business News - Local Los Angeles News | Los Angeles Business from bizjournals 2010

  • "The BSM-2000's detection method for detecting anthrax can also be used for detecting C. difficile, which is also a spore forming bacteria," said Mr. Amir Ettehadieh, UNDT's Director of Research and Development.

    News 2009

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