Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun An enzyme present in muscle tissue that acts in carbohydrate metabolism.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry A
metalloenzyme responsible for thecatalysis ofphosphoglycerate tophosphoenolpyruvate duringglycolysis
Etymologies
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Examples
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For example, there is a distinctive ID hypothesis that predicts that the degradosome functions as a prong in enolase.
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Expression of Cre and hence targeting of the floxed gene can be restricted to e.g. T cells (lck promoter), cardiac muscle (cardiac myosin promoter), neurons (enolase promoter) or epithelia (cytokeratin promoter).
The 2007 Nobel Prize in Physiology or Medicine - Advanced Information 2007
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Heavy atom NMR spectroscopy of the hydrogens of P-enolpyruvate led to Mildred Cohn's solution of the reaction stereochemistry of the reaction of enolase using (3R) - phosphoglyceric acid-3-d39.
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These results demonstrate that malignant cells adapt to hypoxia by modulating alpha-enolase/MBP-1 levels and suggest a mechanism for tumor cell induction of the hyperglycolytic state.
BioMed Central - Latest articles Kara Sedoris 2010
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The alpha-enolase gene encodes both a glycolytic enzyme (alpha-enolase) and a DNA-binding tumor suppressor protein, c-myc binding protein (MBP-1).
BioMed Central - Latest articles Kara Sedoris 2010
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H1-responses to Asp f3 (a putative peroxismal membrane protein), Asp f9/16 (cell wall glucanase), Asp f11 (cyclophilin type peptidyl-prolyl isomerase) and Asp f22 (enolase).
PLoS ONE Alerts: New Articles Neelkamal Chaudhary et al. 2010
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We also observed that the A. fumigatus enolase, rAsp f22, was recognized exclusively by IFN-γ secreting T-cells.
PLoS ONE Alerts: New Articles Neelkamal Chaudhary et al. 2010
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To examine the regulation of alpha-enolase and MBP-1 by a hypoxic microenvironment in breast cancer, MCF-7 cells were grown in low, physiologic, or high glucose under 1% oxygen.
BioMed Central - Latest articles Kara Sedoris 2010
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H1-responses to Asp f3 (a putative peroxismal membrane protein), Asp f9/16 (cell wall glucanase), Asp f11 (cyclophilin type peptidyl-prolyl isomerase) and Asp f22 (enolase).
PLoS ONE Alerts: New Articles Neelkamal Chaudhary et al. 2010
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These divergent alpha-enolase gene products play central roles in glucose metabolism and growth regulation and their differential regulation may be critical for tumor adaptation to hypoxia.
BioMed Central - Latest articles Kara Sedoris 2010
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