Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective Of or pertaining to
euchromatin
Etymologies
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Examples
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The major force driving the degeneration of Y chromosomes are retrotransposons in remodelling former euchromatic chromosome structures into heterochromatic ones.
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The major force driving the degeneration of Y chromosomes are retrotransposons in remodelling former euchromatic chromosome structures into heterochromatic ones.
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However, upon β-catenin stabilization, it associates with β-catenin inside the euchromatic nuclear compartment, and its binding to target DNA is enhanced along with recruitment of β-catenin and H3K9 acetylation.
PLoS Biology: New Articles Dimple Notani et al. 2010
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Knock-down and transfection experiments for DOT1L show that this enzyme has a direct role in maintaining the euchromatic and active status of these genes when unmethylated.
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These findings suggest that DNA demethylating interventions alone are not able to restore a complete euchromatic status and a full transcriptional reactivation of the epigenetically silenced tumor suppressor genes, and reinforce the necessity of targeting multiple elements of the epigenetics machinery for a successful treatment of malignancies.
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Knock-down and transfection experiments for DOT1L show that this enzyme has a direct role in maintaining the euchromatic and active status of these genes when unmethylated.
Naturejobs - All Jobs F V Jacinto 2009
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Our molecular maps demonstrate that heterochromatin can invade a normally euchromatic region, yet the strength of HP1 binding and effects on gene expression are highly dependent on local context.
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These findings suggest that DNA demethylating interventions alone are not able to restore a complete euchromatic status and a full transcriptional reactivation of the epigenetically silenced tumor suppressor genes, and reinforce the necessity of targeting multiple elements of the epigenetics machinery for a successful treatment of malignancies.
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These findings suggest that DNA demethylating interventions alone are not able to restore a complete euchromatic status and a full transcriptional reactivation of the epigenetically silenced tumor suppressor genes, and reinforce the necessity of targeting multiple elements of the epigenetics machinery for a successful treatment of malignancies.
Naturejobs - All Jobs F V Jacinto 2009
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Segmental duplications (SDs) are euchromatic portions of genomic DNA ([greater than or equal to] 1kb) that occur at more than one site within the genome, and typically share a high level of sequence identity (>
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