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Examples
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Prevention organisation CRY cardiac risk in the young said exercise and sport could trigger a condition known as hypotrophic cardiomyopathy.
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That is to say, people who are newly dieting and have overfull fat cells do not suffer from starvation symptoms as extremely as people who have normal sized fat cells or hypotrophic fat cells.
Gary Taubes responds | The Blog of Michael R. Eades, M.D. 2008
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Because of the metabolic changes induced by hypotrophic fat tissue, the obese person is actually starving on a cellular level, even if they appear normal weight or even overweight.
Gary Taubes responds | The Blog of Michael R. Eades, M.D. 2008
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A low carb and cal diet can reduce insulin, get fat out of fat cells… but it does not kill fat cells, so fat cells remain hypotrophic and do not produce leptin normally, even if total fat mass appears “healthy” by charts and BMI range and body fat analysis.
Gary Taubes responds | The Blog of Michael R. Eades, M.D. 2008
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Intuitively I doubt that hCG works via leptin at all… leptin is mostly relevant AFTER weight loss, when cells are hypotrophic and insulin is low.
Gary Taubes responds | The Blog of Michael R. Eades, M.D. 2008
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The leptin deficiency post weight loss/maintenance is related to the former obese individual having hypotrophic (small) fat cells that are hyperplastic (numerous).
Gary Taubes responds | The Blog of Michael R. Eades, M.D. 2008
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