Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective Restricted to a
localized region of thebody .
Etymologies
Sorry, no etymologies found.
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Examples
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Most elderly patients can have surgery to control locoregional disease, but might not be candidates for intensive biologic therapies for advanced melanoma because of comorbidities and inability to tolerate the adverse side effects of these treatments.
Naturejobs - All Jobs Susan Tsai 2010
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There is increasing evidence to include combined neoadjuvant chemoradiotherapy (CRT) as an alternative to surgical resection alone, to improve survival for locoregional esophageal cancer.
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The patients cited in the article were part of the Phase 2 study investigating the effectiveness of PV-10 for locoregional treatment of metastatic melanoma.
THE MEDICAL NEWS Editors 2010
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The rate of locoregional recurrence was 10.4 % after breast-conserving surgery, as compared with 2.5 % after mastectomy.
Naturejobs - All Jobs M Tanioka 2010
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Variations in locoregional therapy in postmenopausal patients with early breast cancer treated in different countries. van Nes et al. British Journal of Surgery. 97 (5), pp 671-679.
Science Blog BJS 2010
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"The fact that locoregional recurrence is still a very strong prognostic factor, even after a long disease-free interval, suggests that it probably is a symptom of (and therefore associated with) distant disease occurring at the same time, and not the instigator of disease progression in the majority of cases," study collaborator Dr. Jos A. van der Hage, a surgical oncologist at the Netherlands Cancer Institute in Amsterdam, said in the news release.
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Rates and patterns of locoregional and distant recurrence did not differ between the two groups.
MedPageToday.com - medical news plus CME for physicians 2010
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At 5 years, the rates of locoregional relapse were 4.9%
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"In patients who were free of disease for more than 10 years after primary treatment, locoregional recurrence had a significant impact on both disease-free survival and overall survival," Dr. Sven Mieog, a research fellow at Leiden University Medical Center in the Netherlands, said in a news release from the European Breast Cancer Conference.
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The full paper includes extensive data on each country, including: eligibility criteria and protocols; comparison of patients and tumour characteristics; locoregional treatment characteristics and analysis of factors associated with type of surgery, including age, BMI and tumour size.
Science Blog BJS 2010
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