Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A length of double-stranded DNA containing two million nucleotides, one million on each strand.
  • noun A length of single-stranded RNA containing one million nucleotides

Etymologies

from Wiktionary, Creative Commons Attribution/Share-Alike License

mega- +‎ base

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Examples

  • A megabase with three rings of security, Bagram serves as a kind of clearinghouse where troops are processed and then airlifted to their frontline positions.

    Life At Bagram 2007

  • If the megabase deletions have subtle effects on fitness, those alleles should drop in frequency. raven

    Let's Talk Junk (Again). - The Panda's Thumb 2007

  • And many of those that "served" in Vietnam were support elements that never set foot in Vietnam Navy, AF bases in adjacent countries or if they were in country, arrived at a safe American megabase like Da Nang and never left it's sanctuary.

    "Webb... has become a pompous poseur and an abuser of the English language before actually becoming a senator." Ann Althouse 2006

  • In a recent paper Nobrega et al, 2004 megabase sections of non-coding DNA, including many conserved repetitive sequences, were deleted from the mouse genome.

    Another example of "scholarship" - The Panda's Thumb 2005

  • These ranged from large genomic amplifications or deletions, such as amplification of the entire 17q arm, to more discrete changes, such as a two-megabase amplification encompassing the MYC oncogene.

    Embryonic Stem Cell Lines Prove Unstable | Impact Lab 2005

  • · Interactive zoom from megabase to nucleotide resolution

    Softpedia - Windows - All 2010

  • Here, we describe a resequencing approach that directs focus to genomic regions of high interest by combining hybridization-based purification of multi-megabase regions with sequencing on the Illumina Genome Analyzer (GA).

    Naturejobs - All Jobs Emily Hodges 2010

  • Broadening the range of manipulatable DNA to megabase scale would be fundamental to deepen the understanding of gene regulation in the chromosomal context.

    PLoS ONE Alerts: New Articles Munehiro Uemura et al. 2010

  • In the 1 megabase interval surrounding but not including rs3698264, the p-values ranged from 0.045 to 0.00083.

    PLoS ONE Alerts: New Articles 2009

  • Recent advances in massively parallel sequencing make it possible to rapidly obtain large amounts of sequence data, and multiplexing makes extensive sampling of megabase sequences feasible.

    BioMed Central - Latest articles 2009

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