Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun A purine analog, C5H4N4S, that acts as an antimetabolite by interfering with purine synthesis, used primarily in the treatment of acute leukemia.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun A particular
oral drug used in the treatment ofcancer .
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- noun a drug (trade name Purinethol) that interferes with the metabolism of purine and is used to treat acute lymphocytic leukemia
Etymologies
Sorry, no etymologies found.
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Examples
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Six weeks later, he gave the boy four courses of high-dose methotrexate, daily mercaptopurine, and four triple-drug treatments into the spinal fluid.
Curing Cancer 2010
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The next regimen they would try would be a combination of all four drugs: vincristine, amethopterin, mercaptopurine, and prednisone.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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The next regimen they would try would be a combination of all four drugs: vincristine, amethopterin, mercaptopurine, and prednisone.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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When a 12-year-old boy from Illinois with ALL arrived at St. Jude in 2001, Pui administered everything but the kitchen sink: the drugs prednisone, vincristine, daunorubicin, and asparaginase, followed by cyclophosphamide, cytarabine, and mercaptopurine.
Curing Cancer 2010
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The next regimen they would try would be a combination of all four drugs: vincristine, amethopterin, mercaptopurine, and prednisone.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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Most can handle standard doses of the drug mercaptopurine.
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The result was azathioprine (1957) which replaced mercaptopurine as an inhibitor of the immune response.
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However, studies with a 6-mercaptopurine-resistant strain of L. casei revealed the 6-MP was unable to utilize hypoxanthine for growth (29).
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The liposomal ld50 of mercaptopurine was compared to fold 480 mg/kg in the and 425 mg/kg in the rat.
Wii-volution 2010
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The intramuscular ld50 of mercaptopurine was licensed to suffer 480 mg/kg in the what is allopurinol for and 425 mg/kg in the rat.
Wii-volution 2010
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