Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun genetics Any substance used to
modify gene expression
Etymologies
Sorry, no etymologies found.
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Examples
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Finally, the control morpholino, which is a five base mismatch of the original MO, did not result in any phenotype, apoptosis or upregulation of the p53 pathway (
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AVI's proprietary, intrinsically charge-neutral, phosphorodiamidate morpholino oligomer PMO
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AVI-7100 employs the Company's patented PMOplus™ technology that selectively introduces positive charges to a phosphorodiamidate morpholino oligomer PMO backbone to improve selective interaction between the drug and its target.
unknown title 2011
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AVI BioPharma is focused on the discovery and development of RNA-based therapeutics utilizing proprietary derivatives of its antisense chemistry (morpholino-modified phosphorodiamidate oligomers or PMOs) that can be applied to a wide range of diseases and genetic disorders through several distinct mechanisms of action.
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Using a PDGFR tyrosine kinase inhibitor, a morpholino oligonucleotide specific to
Elites TV 2010
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AVI BioPharma is focused on the discovery and development of RNA-based drugs utilizing proprietary derivatives of its antisense chemistry (morpholino-modified phosphorodiamidate oligomers or PMOs) that can be applied to a wide range of diseases and genetic disorders through several distinct mechanisms of action.
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RNA and morpholino antisense oligonucleotides were microinjected into the yolk of one-cell stage embryos.
PLoS ONE Alerts: New Articles Ulrike Naumann et al. 2010
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AVI BioPharma is focused on the discovery and development of RNA-based medicines utilizing proprietary derivatives of its antisense chemistry (morpholino-modified phosphorodiamidate oligomers or PMOs) that can be applied to a wide range of diseases and genetic disorders through several distinct mechanisms of action.
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RNA and morpholino antisense oligonucleotides were microinjected into the yolk of one-cell stage embryos.
PLoS ONE Alerts: New Articles Ulrike Naumann et al. 2010
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Upon the introduction of an antisense morpholino (2 mM) against granzyme G to knock-down endogenous gene function, all embryos were arrested at the 2 - to 4-cell stages of egg cleavage, and the de novo synthesis of zygotic RNAs was decreased.
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