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Examples
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Effects on the brain metabolites N-acetyl-L-aspartate, choline and myo-inositol levels have been reported in clinical studies using this drug.
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Biochemical and genetic characterization of the pimB gene from M. tuberculosis have suggested that PimB is the α-D-mannose-α (1→6) - phosphatidyl - myo-inositol monomannoside transferase responsible for the formation of triacyl-PIM2 from GDP-Man and triacyl-PIM1.
PLoS ONE Alerts: New Articles Kushagra Bansal et al. 2009
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Albeit mycobacteria reside within phagolysosomes of the infected macrophages, envelope glycoconjugates like Lipoarabinomannan (LAM), phosphatidyl - myo-inositol mannosides (PIM), Trehalose 6,6′-dimycolate (TDM; cord factor) etc., are released and traffic out of the mycobacterial phagosome into endocytic compartments as well as can gain access to the extracellular environment in the form of exocytosed vesicles
PLoS ONE Alerts: New Articles Kushagra Bansal et al. 2009
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In this study, we investigated the molecular mechanisms underlying Phosphatidyl - myo-inositol dimannosides (PIM2), an integral component of the mycobacterial envelope, triggered COX-2 and MMP-9 expression in macrophages.
PLoS ONE Alerts: New Articles Kushagra Bansal et al. 2009
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+ / myo-inositol cotransporter (SMIT), the sodium-dependent neutral aminoacid transporter 2 (SNAT2), and the Na
PLoS ONE Alerts: New Articles Katherine Drews-Elger et al. 2009
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+-dependent myo-inositol transporter gene in mouse lens led to congenital cataract.
PLoS ONE Alerts: New Articles Anaïs Estrada-Gelonch et al. 2009
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