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Examples
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Once linoleic acid combines with the nitrogen at one of its double bonds, a substance known as nitrolinoleic acid LNO2 is formed.
Forever Young M.D. Nicholas Perricone 2010
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The most exciting action of nitrolinoleic acid, in my opinion, is the upregulation of NRF2, which, as you know, is hugely important, as it protects cells from oxidative stress free-radical damage and subsequent inflammation.
Forever Young M.D. Nicholas Perricone 2010
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Like the omega-3 essential fatty acids, nitrolinoleic acid activates nuclear receptors known as peroxisome proliferator-activated receptors, or PPARs.
Forever Young M.D. Nicholas Perricone 2010
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As exciting as these particular discoveries are, the upregulation of the production of HO-1 is just one of many ways that nitrolinoleic acid provides protection to our bodies.
Forever Young M.D. Nicholas Perricone 2010
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The effects of nitrolinoleic acid on cell mechanisms are currently generating great interest in the scientific world.
Forever Young M.D. Nicholas Perricone 2010
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Continued research has revealed that very low concentrations of nitrolinoleic acid inhibit the expression of various pro-inflammatory genes, blocking the production of cytokines and cytokine receptors.
Forever Young M.D. Nicholas Perricone 2010
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Scientists anticipate that nitrolinoleic acid supplements will confer many systemic benefits, including the prevention of hypertension high blood pressure, diabetes, and stroke, and promoting healthy weight loss.
Forever Young M.D. Nicholas Perricone 2010
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It appears that nitrolinoleic acid strongly binds to and activates PPARs, providing significant protection against the high blood sugar associated with type 2 diabetes while dramatically reducing excess body fat.
Forever Young M.D. Nicholas Perricone 2010
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Weight loss is a particularly fascinating aspect of the action of nitrolinoleic acid.
Forever Young M.D. Nicholas Perricone 2010
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As we have learned, the nitroalkenes—nitrolinoleic acid, for example—strongly bind to and activate the PPARs, resulting in even greater weight loss, partitioning of energy, and uncoupling of oxidative phosphorylation.
Forever Young M.D. Nicholas Perricone 2010
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