open-label

Although several open-label trials on gene therapy have shown promise in treating neurologic disease, the researchers noted that this is the first of its type to be confirmed in a follow-up randomized double-blind trial, a study in which neither the investigators nor the patients knew which patients were receiving the real or sham treatment.

Gene therapy may help reverse Parkinson's symptoms 2011

Announcing the failure of the latest trial Tuesday, the two companies said they would halt development of Dimebon for all indications and cease an ongoing open-label extension study in Alzheimer's disease.

Medivation, Pfizer End Work on Alzheimer's Drug Jonathan D. Rockoff 2012

Although several open-label trials on gene therapy have shown promise in treating neurologic disease, the researchers noted that this is the first of its type to be confirmed in a follow-up randomized double-blind trial, a study in which neither the investigators nor the patients knew which patients were receiving the real or sham treatment.

Gene therapy may help reverse Parkinson's symptoms 2011

“Placebo effect is an enormous problem in open-label studies,” said Dr. Scott Turner, incoming director of the Memory Disorders Program at Georgetown University Medical Center in Washington.

Drug restores speech in Alzheimer’s; experts worry « Isegoria 2008

"Usual versus tight control of systolic blood pressure in non-diabetic patients with hypertension (Cardio-Sis): an open-label randomised trial"

Bad Press for Sleeping Babies 2009

It is in pursuant of these goals that MSD is sponsoring an expanded access, non-comparative, multi-centre, open-label, treatment use study titled "Early Access of MK-0518 in Combination With an Optimised Background Antiretroviral Therapy (OBT) in Highly Treatment Experienced HIV-1 Infected Patients With Limited to No Treatment Options."

Experts Visit Nigeria Over New HIV Drug Trials 2008

Now, data from an open-label extension, which means that doctors and patients know which drugs are being used, show that those benefits continued after six months with no additional side effects.

Data Issued on Medivation Alzheimer's Drug 2008

Tenthoff suggested that higher patient drop-outs may be due to the open-label nature of the trial.

Human Genome Sciences Seen Partnering Hep C Drug In 2006 2006

On Monday morning, the biotech company said results from an ongoing open-label study showed 75% of patients taking the three main constituents of combo pill Atripla maintained a viral load below 400 copies of HIV per milliliter of blood, compared with 62% for patients taking a similar drug marketed by GlaxoSmithKline.

Gilead Seen Poised For Growth 2006

"The focus for the stock, however, remains the potential launch of Tysabri, and our belief that this drug is likely to return to the market in the second quarter was bolstered by Wednesday's announcement that an open-label, safety extension study for the Phase III multiple sclerosis study could begin enrolling in the coming weeks," wrote analyst Steven Harr, in a client note.

Biogen Idec Seen With Near-Term Upside To High $40s 2006