Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun genetics either of a pair of
genes that derives from the sameancestral gene. - noun a pair of genes that derives from the same ancestral gene and now reside at different locations within the same genome.
Etymologies
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Examples
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Strunkelnberg M, Bonengel B, Moda LM, Hertenstein A, de Couet HG, et al. (2001) rst and its paralogue kirre act redundantly during embryonic muscle development in Drosophila.
PLoS ONE Alerts: New Articles Sarada Bulchand et al. 2010
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There are examples of other paralogue genes in zebrafish showing differences in expression patterns
PLoS ONE Alerts: New Articles Gayathri Chandrasekar et al. 2010
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This process requires the functions of various molecules including the transmembrane myoblast attractants Dumbfounded (Duf) and its paralogue Roughest (Rst), a scaffold protein Rolling pebbles (Rols) and a guanine nucleotide exchange factor Loner.
PLoS ONE Alerts: New Articles Sarada Bulchand et al. 2010
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This process requires the functions of various molecules including the transmembrane myoblast attractants Dumbfounded (Duf) and its paralogue Roughest (Rst), a scaffold protein Rolling pebbles (Rols) and a guanine nucleotide exchange factor Loner.
PLoS ONE Alerts: New Articles Sarada Bulchand et al. 2010
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Researchers have therefore increased the severity of the murine dystrophin-deficiency phenotype by creating double mutants: either mice lacking both dystrophin and its paralogue, utrophin, or both dystrophin and MyoD (a transcription factor important in muscle development and regeneration) [18], [26].
PLoS ONE Alerts: New Articles Gemma L. Walmsley et al. 2010
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The FCs express the myoblast attractants, Dumbfounded (Duf)/Kin of irregular-chiasm-C (Kirre) and its paralogue Roughest (Rst)/Irregular chiasm-C (IrreC)
PLoS ONE Alerts: New Articles Sarada Bulchand et al. 2010
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Molecular evolutionary analyses indicated that: rln3a, rln3b and rln are under strong evolutionary constraint, that insl3 has been subject to moderate rates of sequence evolution with two amino acids in insl3/INSL3 showing evidence of positively selection, and that insl5b exhibits a higher rate of sequence evolution than its paralogue insl5a suggesting that it may have been neo-functionalized after the teleost whole genome duplication.
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Molecular evolutionary analyses indicated that: rln3a, rln3b and rln are under strong evolutionary constraint, that insl3 has been subject to moderate rates of sequence evolution with two amino acids in insl3/INSL3 showing evidence of positively selection, and that insl5b exhibits a higher rate of sequence evolution than its paralogue insl5a suggesting that it may have been neo-functionalized after the teleost whole genome duplication.
BioMed Central - Latest articles Sara Good-Avila 2009
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The homB gene is a Helicobacter pylori disease marker candidate, strongly associated with peptic ulcer disease, while homA, its paralogue gene with 90% sequence identity, is correlated with non ulcer dyspepsia.
BioMed Central - Latest articles Monica Oleastro 2009
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Molecular evolutionary analyses indicated that: rln3a, rln3b and rln are under strong evolutionary constraint, that insl3 has been subject to moderate rates of sequence evolution with two amino acids in insl3/INSL3 showing evidence of positively selection, and that insl5b exhibits a higher rate of sequence evolution than its paralogue insl5a suggesting that it may have been neo-functionalized after the teleost whole genome duplication.
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