Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry A large multidomain proteoglycan.

Etymologies

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Examples

  • It is believed that proteoglycans such as perlecan, which are rich in the sulphated glycosaminoglycan heparan sulphate, play an important role in the retention of lipoproteins to endothelial extracellular matrix.

    PLoS ONE Alerts: New Articles Alan D. Pemberton et al. 2010

  • Golgi-mediated glycosylation events were altered in fibroblasts and chondrocytes lacking GMAP-210, and these chondrocytes had intracellular accumulation of perlecan, an extracellular matrix protein, but not of type II collagen or aggrecan, two other extracellular matrix proteins.

    Medlogs - Recent stories 2010

  • Golgi-mediated glycosylation events were altered in fibroblasts and chondrocytes lacking GMAP-210, and these chondrocytes had intracellular accumulation of perlecan, an extracellular matrix protein, but not of type II collagen or aggrecan, two other extracellular matrix proteins.

    Medlogs - Recent stories 2010

  • Golgi-mediated glycosylation events were altered in fibroblasts and chondrocytes lacking GMAP-210, and these chondrocytes had intracellular accumulation of perlecan, an extracellular matrix protein, but not of type II collagen or aggrecan, two other extracellular matrix proteins.

    Medlogs - Recent stories 2010

  • Golgi-mediated glycosylation events were altered in fibroblasts and chondrocytes lacking GMAP-210, and these chondrocytes had intracellular accumulation of perlecan, an extracellular matrix protein, but not of type II collagen or aggrecan, two other extracellular matrix proteins.

    Medlogs - Recent stories 2010

  • Golgi-mediated glycosylation events were altered in fibroblasts and chondrocytes lacking GMAP-210, and these chondrocytes had intracellular accumulation of perlecan, an extracellular matrix protein, but not of type II collagen or aggrecan, two other extracellular matrix proteins.

    Medlogs - Recent stories 2010

  • Indeed, ApoE knockout mice which were also deficient in perlecan-associated heparan sulphate were found to be protected from development of atherosclerosis, compared to heparan sulphate sufficient controls

    PLoS ONE Alerts: New Articles Alan D. Pemberton et al. 2010

  • Golgi-mediated glycosylation events were altered in fibroblasts and chondrocytes lacking GMAP-210, and these chondrocytes had intracellular accumulation of perlecan, an extracellular matrix protein, but not of type II collagen or aggrecan, two other extracellular matrix proteins.

    Medlogs - Recent stories 2010

  • Tran-Lundmark K, Tran PK, Paulsson-Berne G, Friden V, Soininen R, et al. (2008) Heparan sulfate in perlecan promotes mouse atherosclerosis: roles in lipid permeability, lipid retention, and smooth muscle cell proliferation.

    PLoS ONE Alerts: New Articles Alan D. Pemberton et al. 2010

  • Golgi-mediated glycosylation events were altered in fibroblasts and chondrocytes lacking GMAP-210, and these chondrocytes had intracellular accumulation of perlecan, an extracellular matrix protein, but not of type II collagen or aggrecan, two other extracellular matrix proteins.

    Medlogs - Recent stories 2010

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