Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun Any
molecule that has aradioactive tracer attached, especially one used forradioimmunoassay
Etymologies
Sorry, no etymologies found.
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Examples
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[11C] befloxatone is a high-affinity, reversible, and selective radioligand for the in vivo visualization of the monoamine oxidase A (MAO-A) binding sites using positron emission tomography (PET).
Naturejobs - All Jobs Michel Bottlaender 2010
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You will need to have good knowledge of cell signalling, signal transduction and the development of radioligand binding assays as well as cell signalling assays.
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- Characterisation of target molecules using radioligand and fluorescent binding
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The interactions of lanzoprazole and astemizole with the anomalous tau aggregates were assessed by classical radioligand assays, combined with surface plasmon resonance, bioinformatic approaches and immunofluorescence studies on isolated PHFs and brain samples from Alzheimer's cases.
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For radioligand binding, media was removed and cells washed once with 10 ml PBS.
PLoS ONE Alerts: New Articles Eiron Cudaback et al. 2010
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Gonsiorek W, Hesk D, Chen SC, Kinsley D, Fine JS, et al. (2006) Characterization of peripheral human cannabinoid receptor (hCB2) expression and pharmacology using a novel radioligand, [35S] Sch225336.
PLoS ONE Alerts: New Articles Eiron Cudaback et al. 2010
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Quantification of CB1 and CB2 receptor proteins by radioligand binding showed a correlation between the relative level of mRNA encoding each receptor and the corresponding protein expression level as expressed by the B
PLoS ONE Alerts: New Articles Eiron Cudaback et al. 2010
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They also saw effects on a radioligand binding assay to the GABA-A receptor, and they point out that the biocides used are known to show substantial protein and DNA binding.
In the Pipeline 2008
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