Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective Of or pertaining to
tranexamic acid or its derivatives
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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Medicine tested an off-patent treatment called tranexamic acid (TXA) among 20,000 severely-injured adults in 274 hospitals in 40 countries.
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Three years ago Henderson was fined £40,000 and banned from making race entries for three months after Moonlit Path, owned by the Queen, tested positive for tranexamic acid, a banned blood-clotting agent.
Nicky Henderson craves Cheltenham Gold Cup at end of troubled Festival 2011
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Trasylol costs $1,300 per use, compared with $44 for aminocaproic acid and $11 for tranexamic acid, says lead author Dennis Mangano, head of the Ischemia Research and Education Foundation in San Bruno, Calif.
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The new, multi-center international study compared the death rates of four groups of patients who had undergone bypass surgery: 1,072 given Trasylol, 834 given aminocaproic acid; 442 given tranexamic acid and 1,374 who didn't receive any medication to prevent excessive bleeding.
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The study found that 6% of patients who received Trasylol, or aprotinin, died within 30 days of surgery compared to 4% of patients who received tranexamic acid or aminocaproic acid.
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The study's control group of 1,374 patients, received a placebo, while 1,295 patients received Trasylol, 883 others received aminocaproic, and 822 patients received tranexamic.
Drug Alert - Trasylol Blamed For Lethal Injuries During Surgery 2006
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The study data was gathered from patients who had surgery between 1996 and 2000, at more than 69 medical centers around the world, and received either Trasylol, aminocaproic acid, tranexamic acid, or no drug treatment.
Drug Alert - Trasylol Blamed For Lethal Injuries During Surgery 2006
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As far as these large trials go, tranexamic acid was a success.
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The drug, tranexamic acid, stops bleeding by helping the blood clot.
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Although the CRASH-2 trial was well done, Simon said that because it was not conducted in the U.S., American doctors will be more reluctant to adopt tranexamic acid as a treatment for their trauma patients.
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