Silenor

The company says that, unlike Silenor, antihistamines like Benadryl don't strongly hit the specific histamine receptor that is closely associated with sleep.

Dawn of A New Sleep Drug? Andrea Petersen 2011

Somaxon's Silenor, approved for use by those who have trouble staying asleep at night, can cause drowsiness, the company said.

Dawn of A New Sleep Drug? Andrea Petersen 2011

Last fall, Somaxon Pharamaceuticals Inc. launched Silenor, a drug that blocks histamine receptors, which are important in regulating wakefulness.

Dawn of A New Sleep Drug? Andrea Petersen 2011

The active ingredient in Silenor, doxepin, has been used for years in higher doses as an antidepressant.

Dawn of A New Sleep Drug? Andrea Petersen 2011

Silenor is the first product on the market for Somaxon, which focuses on disorders of the central nervous system.

Headwaters 2010

Somaxon's product Silenor, now available by prescription in the United States, is indicated for the treatment of insomnia characterized by difficulty with sleep maintenance.

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As a result of the discontinuation of co-promotion services under the Procter & Gamble agreement, Procter & Gamble will be entitled to a low single-digit royalty on net sales of Silenor for the 2012 fiscal year.

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Discussion during the conference call may include forward-looking statements regarding such topics as, but not limited to, the company's commercial plans and activities relating to Silenor, prescription trends, the company's financial status and performance, the potential to develop an OTC version of Silenor, and any comments the company may make about its future plans or prospects in response to questions from participants on the conference call.

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Last month Somaxon and Pro Com One Inc filed a lawsuit against India's Zydus Cadila challenging its application to make a copycat version of Somaxon's insomnia drug, Silenor.

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"The changes to the Procter & Gamble agreement represent the natural evolution of our relationship at this stage in Silenor's commercial growth, allowing us to reallocate resources from sales support toward Silenor consumer awareness initiatives, while continuing to explore the potential for a Silenor OTC life cycle management opportunity with a highly differentiated label," continued Pascoe.

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