Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun A derivative of
tetracycline , having noantibiotic activity, that is used in experimentalgenetics
Etymologies
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Examples
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Systematic name anhydrotetracycline, NADPH: oxygen oxidoreductase (6-hydroxylating) Recommended name anhydrotetracycline monooxygenase Synonyms ATC oxygenase anhydrotetracycline oxygenase oxygenase, anhydrotetracycline CAS registry number 70766-62-0 2 Source Organism
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The experiments performed in a shake flask fed-batch system (EnBase (R)) verified earlier observations that cell density and oxygen supply are critical factors for the use of the inducer anhydrotetracycline and thus for the soluble C-P4H yield.
BioMed Central - Latest articles Ekaterina Osmekhina 2010
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Adding anhydrotetracycline (ATc) to the cell culture in measured doses stifles the tetracycline repressor and permits expression of yEGFP.
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Novotna, J.; Neuzil, J.; Behal, V.: Partial purification and characterization of anhydrotetracycline oxyge - nase of Streptomyces aureofaciens.
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Streptomyces aureofaciens (50/137, UV-light induced mutant of strain 84/25 [1-4]; high - and low-production strain [5]) [1-7] 3 Reaction and Specificity Catalyzed reaction anhydrotetracycline + NADPH + H+ + O2 = 12-dehydrotetracycline + NADP+ + H2 O Reaction type oxidation redox reaction reduction Natural substrates and products S anhydrotetracycline +
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Effect of tetracycline derivates and some cations on the activity of anhydrotetracycline oxygenase.
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Neuzil, J.; Novotna, J.; Vlach, J.; Behal, V.: Isolation of pure anhydrotetracycline oxygenase from Streptomyces aureofa - ciens.
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(anhydrotetracycline) [2] pH-Optimum 7. 3-7.4 (assay at [1,3,4]) [1, 3, 4] Temperature optimum (C) 28
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32, 411-416 (1987) [6] Behal, V.; Gregrova-Prusakova, J.; Hostalek, Z.: Effect of inorganic phosphate and benzyl thiocyanate of the activity of anhydrotetracycline oxygenase in Streptomyces aureofaciens.
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