Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A lactam composed of a four-membered ring, formed by intramolecular condensation of an amino acid in which the amino group is located at the beta position, or any compound containing this group.
  • noun Any of a class of broad-spectrum antibiotics, such as certain penicillins and cephalosporins, that contain a lactam ring.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun organic chemistry A lactam having a four-membered ring structure; a structural element of many antibiotics such as penicillin.

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[beta, second (in the series of lactam rings, the first being the simplest) + lactam, a cyclic amide (lact(one) + am(ide)).]

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Examples

  • Collectively, they are called beta-lactam antibiotics and are the most commonly prescribed drugs in medicine.

    SUPERBUG MARYN MCKENNA 2010

  • Collectively, they are called beta-lactam antibiotics and are the most commonly prescribed drugs in medicine.

    SUPERBUG MARYN MCKENNA 2010

  • Collectively, they are called beta-lactam antibiotics and are the most commonly prescribed drugs in medicine.

    SUPERBUG MARYN MCKENNA 2010

  • What all of these have in common is a four-cornered arrangement of atoms at the center of the drug molecule, called the beta-lactam ring.

    SUPERBUG MARYN MCKENNA 2010

  • What all of these have in common is a four-cornered arrangement of atoms at the center of the drug molecule, called the beta-lactam ring.

    SUPERBUG MARYN MCKENNA 2010

  • What all of these have in common is a four-cornered arrangement of atoms at the center of the drug molecule, called the beta-lactam ring.

    SUPERBUG MARYN MCKENNA 2010

  • Ampicillin and amoxicillin, semi-synthetic penicillins that were developed more recently, also incorporate the beta-lactam ring.

    SUPERBUG MARYN MCKENNA 2010

  • She was started on a beta-lactam antibiotic that could target multiple families of bacteria, another common measure because preemies are so vulnerable to infection.

    SUPERBUG MARYN MCKENNA 2010

  • And all four had been given antibiotics—but because their doctors did not imagine that MRSA was out in the community, the children got beta-lactam antibiotics that would have had no effect on any MRSA strain.

    SUPERBUG MARYN MCKENNA 2010

  • He diagnosed mastitis and possibly shingles, and he prescribed painkillers, an antiviral, and cephalexin, a beta-lactam cephalosporin.

    SUPERBUG MARYN MCKENNA 2010

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