Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun An active, complex enzyme consisting of an apoenzyme and a coenzyme.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry A haloenzyme.

Etymologies

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Examples

  • The overall shape of a sequence of the molecules in a particular stretch of DNA is such that it combines with a molecule (or collection of molecules) that we designate "RNA polymerase", to form a holoenzyme that catalyzes the addition of a particular ribonucleotide to a string of nucleotides, which we call "RNA".

    Attached to Strings 2009

  • The tRNA is combined with a particular amino acid; the holoenzyme catalyzes the transfer of the amino acid to the amino acid string attached to another part of the holoenzyme.

    Attached to Strings 2009

  • The tRNA is combined with a particular amino acid; the holoenzyme catalyzes the transfer of the amino acid to the amino acid string attached to another part of the holoenzyme.

    Attached to Strings 2009

  • The overall shape of a sequence of the molecules in a particular stretch of DNA is such that it combines with a molecule (or collection of molecules) that we designate "RNA polymerase", to form a holoenzyme that catalyzes the addition of a particular ribonucleotide to a string of nucleotides, which we call "RNA".

    Attached to Strings 2009

  • The RNA, suitably edited, leaves the nucleus to combine with a ribosome and a tRNA, to form yet another holoenzyme.

    Attached to Strings 2009

  • The RNA, suitably edited, leaves the nucleus to combine with a ribosome and a tRNA, to form yet another holoenzyme.

    Attached to Strings 2009

  • It is interesting to stress that the lower physical chemical stability of hybrid holoenzyme complexes does not raises functionality problems.

    A Top-down Approach 2008

  • E, et al. (1996) RNA polymerase II holoenzyme contains SWI/SNF regulators involved in chromatin remodeling.

    PLoS Biology: New Articles Francesca De Santa et al. 2010

  • Fellows J, Li Y, de Bizemont T, Dirac AMG, et al. (1999) Elongator, a multisubunit component of a novel RNA polymerase II holoenzyme for transcriptional elongation.

    PLoS ONE Alerts: New Articles Moran Valensi-Kurtz et al. 2010

  • Beckett D (2000) Function of a conserved sequence motif in biotin holoenzyme synthetases.

    PLoS ONE Alerts: New Articles Vibha Gupta et al. 2010

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