Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective genetics, of a mutation causing a partial loss of
gene function.
Etymologies
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Examples
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Pten hypomorphic and a wild-type (wt) allele; hy/−, mice having a
Naturejobs - All Jobs Andrea Alimonti 2010
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Pten hypomorphic and null allele; +/−, mice having a Pten wt and null allele.
Naturejobs - All Jobs Andrea Alimonti 2010
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However, it did cause the formation of hypomorphic limbs as a result of increased cellular condensation and apoptosis.
BioMed Central - Latest articles Jean-Charles Guimond 2010
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Pten hypomorphic and null allele; +/−, mice having a Pten wt and null allele.
Naturejobs - All Jobs Andrea Alimonti 2010
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The inhibition of sonic hedgehog signaling with cyclopamine caused hypomorphic limbs (during development and regeneration) but did not affect the expression of BMP-2 and SOX-9.
BioMed Central - Latest articles Jean-Charles Guimond 2010
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The inhibition of sonic hedgehog signaling with cyclopamine caused hypomorphic limbs (during development and regeneration) but did not affect the expression of BMP-2 and SOX-9.
BioMed Central - Latest articles Jean-Charles Guimond 2010
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However, it did cause the formation of hypomorphic limbs as a result of increased cellular condensation and apoptosis.
BioMed Central - Latest articles Jean-Charles Guimond 2010
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Taken together, these two latter findings have challenged the concept that Wnt signalling in osteoblasts is a key pathway for the regulation of bone formation, which was further underscored by the finding that the osteopenia of rs/rs mice, carrying a hypomorphic mutation of the Wnt co-receptor Lrp6, is caused by increased bone resorption
PLoS ONE Alerts: New Articles Jochen Schulze et al. 2010
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However, it did cause the formation of hypomorphic limbs as a result of increased cellular condensation and apoptosis.
BioMed Central - Latest articles Jean-Charles Guimond 2010
-
The inhibition of sonic hedgehog signaling with cyclopamine caused hypomorphic limbs (during development and regeneration) but did not affect the expression of BMP-2 and SOX-9.
BioMed Central - Latest articles Jean-Charles Guimond 2010
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