octapeptide

It is now commonly accepted that there are a group of peptides such as somatostatin (49, 50), substance P (51), vasoactive intestinal peptide (52) and cholecystokinin or its C-terminal octapeptide

Nobel Lecture Radioimmunoassay: A Probe For Fine Structure Of Biologic Systems 1977

In the case of CCK and its COOH-terminal octapeptide (CCK-8), both of which are biologically active, cleavage to the smaller form occurs at the COOH-terminal side of a single arginine residue (40).

Nobel Lecture Radioimmunoassay: A Probe For Fine Structure Of Biologic Systems 1977

We extended these studies and demonstrated that the peptides in the brain are not from the gastrin family or simply CCK-like, but are in fact intact cholecystokinin (CCK) and its COOH-terminal octapeptide (CCK-8) (43-45).

Nobel Lecture Radioimmunoassay: A Probe For Fine Structure Of Biologic Systems 1977

Sanvar (R) (vapreotide acetate) is a synthetic octapeptide analogue of the naturally-occurring somatostatin hormone.

Medlogs - Recent stories 2008

OVA is processed to the presenting octapeptide (257-264), SIINFEKL, through proteasomal and non-proteasomal activities. 2 As with peptides naturally presented by H-2Kb, SIINFEKL has on its 5th position an amino acid with an aromatic side chain (Phe) and on the 8th position, an aliphatic side chain (Leu) .3 Variants of this peptide consisting of substituting different amino acids at strategic positions have yielded valuable information on the interaction of this peptide and the MHC complex. 3

The Earth Times Online Newspaper 2009

OVA is processed to the presenting octapeptide (257-264), SIINFEKL, through proteasomal and non-proteasomal activities. 2 As with peptides naturally presented by H-2Kb, SIINFEKL has on its 5th position an amino acid with an aromatic side chain (Phe) and on the 8th position, an aliphatic side chain (Leu) .3 Variants of this peptide consisting of substituting different amino acids at strategic positions have yielded valuable information on the interaction of this peptide and the MHC complex. 3

The Earth Times Online Newspaper 2009

OVA is processed to the presenting octapeptide (257-264), SIINFEKL, through proteasomal and non-proteasomal activities. 2 As with peptides naturally presented by H-2Kb, SIINFEKL has on its 5th position an amino acid with an aromatic side chain (Phe) and on the 8th position, an aliphatic side chain (Leu) .3 Variants of this peptide consisting of substituting different amino acids at strategic positions have yielded valuable information on the interaction of this peptide and the MHC complex. 3

The Earth Times Online Newspaper 2009