Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun Alternative spelling of
estrone .
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- noun a naturally occurring weak estrogenic hormone secreted by the mammalian ovary; synthesized (trade name Estronol) and used to treat estrogen deficiency
Etymologies
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Examples
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Butenandt named this substance folliculine, a designation which was later changed to oestrone.
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In 1932, Butenandt was able, from observations made in spectral analysis, and especially on the basis of the then established correct formula of cholesterol to draw up the formulae of the chemical structure of oestrone and oestriol.
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In the process of purification it proved that the male hormone behaved in many respects like oestrone; when he realized this, it made Butenandt's work considerably easier.
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Butenandt confirmed Marrian's discovery and explained the relationship between the new substance and oestrone.
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It differs from oestrone only in the additional content of 1 methyl group and 5 hydrogen atoms.
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Shortly after the discovery of oestrone, Marrian in London (1930) isolated from the urine of pregnant women a new hormone which he called oestriol.
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In 1929 he isolated oestrone in pure, crystalline form, almost at the same time that
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In 1929-1930 he succeeded in isolating oestrone, a feat independently accomplished at about the same time by Butenandt in
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From about the 40th day of pregnancy, the foetal-placental unit of pregnant mares start to produce increasing amounts of oestrone sulphate, which enters the mare's blood and urine.
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The two chemical hormones commonly measured to provide information on the pregnancy status of miniature mares are pregnant mare serum gonadotrophin (PMSG), which is frequently now called chorionic gonadotrophin (eCG), and oestrone sulphate (see main story for more information).
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