Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun A white poisonous glycoside, C29H44O12, extracted from the seeds of several African trees of the genera Strophanthus and Acokanthera, that is used as a dart poison in some parts of Africa.
from The Century Dictionary.
- noun A glucoside which exists in the root and wood of ouabaio (wabaio), Acokanthera ouabaio, from which is prepared the arrow-poison of the Somalis of the east coast of Africa.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun g-
strophanthin , apoisonous cardiac glycoside .
Etymologies
from The American Heritage® Dictionary of the English Language, 4th Edition
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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The active principle is a chemical called ouabain, and it is a powerful stimulant of the muscles of the heart.
The Serpent and the Rainbow Wade Davis 1985
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Ph.D. thesis research on the effects of experimental congestive heart failure, asphyxia and ouabain on high energy phosphates and creatine content of the guinea pig heart.
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Myers, Widespread occurrence in frogs and toads of skin compounds interacting with the ouabain site of Na+, K+, ATPase, Science 208 1980: 503-5; Kennedy, A.
The Serpent and the Rainbow Wade Davis 1985
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In moderate dosage ouabain is used today to treat emergency heart failure; in excessive doses it makes the heart go crazy, pumping wildly until it collapses.
The Serpent and the Rainbow Wade Davis 1985
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Acokanthera shrub, which has bark filled with "ouabain", closely-related to a source of arrow poison famously used to kill elephants.
USATODAY.com News 2011
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Such mastication appears to liberate the ouabain from the bark and mix it with saliva to form a coarse colloid, which is then specifically applied only to the lateral line hairs.
USATODAY.com News 2011
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"It's been known for a long time that injecting the sodium/potassium pump inhibitor ouabain into the brain can induce seizures in rats," says Clapcote, and it's also known that mice lacking two of three forms of the pump - either the "alpha1" or "alpha2" forms - are free from seizures.
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Action of ouabain on submaxillary secretion in the dog
xml's Blinklist.com 2008
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Figure 5C, the application of 0.1 mM ouabain for 1 min substantially reduces the massive postplateau hyperpolarizations in membrane-tethered δ-ACTX-Hv1a-expressing lLN
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The continued increase in ouabain effect following washout is likely due to slow tissue diffusion of the hydrophobic drug.
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