Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun organic chemistry The
inositol ester ofphosphoric acid that is a component ofphosphatidylinositols
Etymologies
Sorry, no etymologies found.
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Examples
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Both compounds target an enzyme called phosphoinositide-3 kinase, or PI3K.
San Jose Business News - Local San Jose News | The Silicon Valley / San Jose Business Journal 2009
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PTEN plays a vital role in the suppression of humans cancers by inhibiting a genetic pathway called phosphoinositide-3 kinase (PI3K).
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PTEN plays a vital role in the suppression of humans cancers by inhibiting a genetic pathway called phosphoinositide-3 kinase (PI3K).
R&D Mag - News 2010
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* The phosphoinositide 3-phosphatase PTEN is known to play a role in the regulation of insulin signaling.
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Progenics' pipeline candidates include PSMA ADC, a human monoclonal antibody-drug conjugate in phase 1 testing for treatment of prostate cancer, and preclinical stage novel multiplex phosphoinositide 3-kinase PI3K inhibitors for the treatment of cancer.
unknown title 2011
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As Akt pathway has been associated with survival and proliferation, Akt inhibition in the phosphoinositide 3-kinase PI3K pathway is an attractive approach for treating disorders 1 characterized by uncontrolled growth of cell, e.g. - cancer
unknown title 2011
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Keryx is developing KRX-0401 (perifosine), a novel, potentially first-in-class, oral anti-cancer agent that inhibits Akt activation in the phosphoinositide 3-kinase (PI3K) pathway, and also affects other signal transduction pathways, including the JNK pathway, believed to be associated with cell death, growth, differentiation and survival.
unknown title 2011
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Prevents blood clots that cause strokes and heart attacks by inhibiting the enzyme phosphoinositide 3-kinase.
Wil's Ebay E-Store amp;34;Acai Berry 2010
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Prevents blood clots that cause strokes and heart attacks by inhibiting the enzyme phosphoinositide 3-kinase.
Wil's Ebay E-Store amp;34;Acai Berry 2010
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Food and Drug Administration (FDA) granted Fast Track designation for perifosine, a novel, potentially first-in-class, oral anti - cancer agent that inhibits the phosphoinositide
THE MEDICAL NEWS Editors 2010
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