screw up

from Wiktionary, Creative Commons Attribution/Share-Alike License.

• verb transitive To tighten or secure with screws.
• verb transitive To raise (rent, fees, etc.) to extortionate levels.
• verb transitive To twist into a contorted state
• verb transitive, colloquial To make a mess of; to ruin.
• verb intransitive, colloquial To blunder; to make a mistake.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

• verb twist into a strained configuration
• verb make more intense
• verb screw or turn higher
• verb make a mess of, destroy or ruin