site-directed

Smith's work forms the basis for site-directed mutagenesis, a technique by which it is possible to change a specific amino-acid in a protein and thereby illuminate its functional role.

The Nobel Prize in Chemistry: The Development of Modern Chemistry 2010

You can do what you want in yeast using a flavour of site-directed mutagenesis.

Design, mutate and freze Pedro Beltrao 2008

I assumed that he (and joy, for that matter) was suggesting that site-directed mutagenesis or other molecular biology methods could design complicated structures de novo – which just exaggerates the capabilities of molecular biology to an absurd degree.

Creationism, defined 2006

Yes, but site-directed mutagenesis is not the same as either evolution or ID – it's a special and limited case.

Creationism, defined 2006

I assumed that he (and joy, for that matter) was suggesting that site-directed mutagenesis or other molecular biology methods could design complicated structures de novo – which just exaggerates the capabilities of molecular biology to an absurd degree.

Creationism, defined 2006

Yes, but site-directed mutagenesis is not the same as either evolution or ID – it's a special and limited case.

Creationism, defined 2006

The Cerulean fluorescent probe was developed by site-directed mutagenesis of enhanced cyan fluorescent protein to yield a higher extinction coefficient and improved quantum yield.

Archive 2005-10-01 2005

In the case of Pol 1, the promise has already borne fruit: After eight rounds of optimizing selection and a little site-directed tinkering, it gave rise to Evolved Pol 1, the strongest polymerase ribozyme yet reported.

Good Math, Bad Math, and David Berlinkski - The Panda's Thumb 2006

Isolation and amplification of a specific gene was one of the outstanding problems in DNA technology, including site-directed mutagenesis, until 1985 when Kary Mullis presented the Polymerase Chain Reaction, now commonly known as

The Nobel Prize in Chemistry 1993 - Presentation Speech 1997

This method of site-directed mutagenesis has created completely new opportunities to study the properties of protein molecules: how they function as catalysts or as signal transmitters through membranes, which factors determine how they fold into specific three-dimensional structures and how they interact with other molecules in the cell.

The Nobel Prize in Chemistry 1993 - Presentation Speech 1997