sulphadoxine

A recent study revealed that resistance by the malaria parasite to pyrimethamine and sulphadoxine drug combination, was widespread, and far more so than previously thought.

ANC Daily News Briefing 2003

Many countries then averted to using sulphadoxine-pyrimethamine (SP), also known as Fansidar, but resistance to that is also spreading.

ANC Daily News Briefing 2002

· Ampoule with 200 mg of sulphadoxine + 10 mg of pyrimethamine/ml

Chapter 11 1993

- Pyrimethamine-sulphadoxine (Fansidar) · Tablet with 500 mg of sulphadoxine + 25 mg of pyrimethamine, orally

Chapter 11 1993

Two thousand four hundred and fifty-one children aged 3-59 months were randomly allocated to four groups to receive: three days of artesunate plus amodiaquine (AS+AQ) monthly, three days of AS+AQ bimonthly, one dose of sulphadoxine-pyrimethamine (SP) bi-monthly or placebo.

PLoS ONE Alerts: New Articles Lesong Conteh et al. 2010

Two thousand four hundred and fifty-one children aged 3-59 months were randomly allocated to four groups to receive: three days of artesunate plus amodiaquine (AS+AQ) monthly, three days of AS+AQ bimonthly, one dose of sulphadoxine-pyrimethamine (SP) bi-monthly or placebo.

PLoS ONE Alerts: New Articles Lesong Conteh et al. 2010

IPTc with sulphadoxine-pyrimethamine (SP) plus artesunate (AS), SP plus three daily doses of amodiaquine (AQ) or SP alone is an efficacious and safe intervention for reducing the burden of malaria in children in high transmission areas with short transmission periods

PLoS ONE Alerts: New Articles Lesong Conteh et al. 2010

Shulman CE, Dorman EK, Cutts F, Kawuondo K, Bulmer JN, et al. (1999) Intermittent sulphadoxine-pyrimethamine to prevent severe anaemia secondary to malaria in pregnancy: a randomised placebo-controlled trial.

PLoS ONE Alerts: New Articles Ricardo Águas et al. 2009

Malar J 6: 88. van Eijk AM, Ayisi JG, ter Kuile FO, Otieno JA, Misore AO, et al. (2004) Effectiveness of intermittent preventive treatment with sulphadoxine-pyrimethamine for control of malaria in pregnancy in western Kenya: a hospital-based study.

PLoS ONE Alerts: New Articles Ricardo Águas et al. 2009

A change in chemotherapy is likely to have played a substantial role - until 2004, chloroquine alone was mainly used but as parasite resistance to this drug had increased to high levels, the first-line treatment of choice became sulphadoxine plus pyrimethamine (SP) combined with chloroquine, from early 2005 onwards.

Health News from Medical News Today 2008