Definitions
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Etymologies
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Examples
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Gene expression analyses revealed that a set of genes involved in cell cycle arrest and DNA repair were differentially regulated in LNCaP and C4-2 in response to radiation, which was also consistent with the radiation-resistant property observed in C4-2 cells.
Naturejobs - All Jobs Bang-Xiang Xie 2010
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In our study, the response to radiation was evaluated in both LNCaP and C4-2.
Naturejobs - All Jobs Bang-Xiang Xie 2010
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Not only can the LNCaP and C4-2 PCa progression model be applied for investigating androgen-refractory progression, but it can also be used to explore the development of radiation resistance in PCa.
Naturejobs - All Jobs Bang-Xiang Xie 2010
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Results showed that C4-2 cells were more likely to survive from irradiation and appeared more aggressive in their resistance to radiation treatment compared with LNCaP, as measured by clonogenic assays and cell viability and cell cycle analyses.
Naturejobs - All Jobs Bang-Xiang Xie 2010
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Mass phenotype structures did usually not show invasion of the lrECM; however, formation of filopodia or pseudopodia was consistently observed in the 22rV1 and occasionally in the LNCaP and RWPE-2 cell lines.
PLoS ONE Alerts: New Articles Ville Härmä et al. 2010
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LNCaP parent line under androgen-depleted condition and had acquired androgen-refractory characteristics.
Naturejobs - All Jobs Bang-Xiang Xie 2010
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The proliferation of human prostate cancer cell lines, both androgen sensitive (LNCaP) and androgen insensitive (PC-3), is inhibited by allium derivatives from garlic in a dose-dependent fashion (6).
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In vitro data show that GATA-2 is directly recruited to the promoter region of the AR upon androgen stimulation of LNCaP prostate cancer cells with 5
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The investigators developed a molecular clone of XMRV, called pXMRV1 and demonstrated that it could replicate in LNCaP cells.
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Construction of pETE vector and KRC / Y and LNCaP cell lines producing tetracycline trans-activator tTA were described in ref.
PLoS ONE Alerts: New Articles Vladimir I. Kashuba et al. 2009
biocon commented on the word LNCaP
LNCaP is an acronym denoting cells of Lymph Node Carcinoma Prostatae. These constitute a repeatedly perpetuated line of cells used in research, which was originally procured from a patient whose lymph nodes exhibited carcinoma prostatae (cancer of the prostate). LNCaP cells are dependent on androgen for proliferation. Another type of prostatic cell, exemplified by the cell line, DU–145, is independent of androgen (insensitive or refractory to androgen) in its proliferation.
March 19, 2016