Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun An amino acid, C5H9NO2, that is found in most proteins and is a major constituent of collagen.

from The Century Dictionary.

  • noun Pyrrolidine carboxylic acid, C4H8N.CO2H, a compound formed by the hydrolysis of the glycylanhydrid obtained bv the tryptic digestion of gelatin. The active a-proline melts at 205° C.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry A nonessential amino acid C5H9NO2 found in most animal proteins, especially collagen; its cyclic structure leads to kinks in the peptide chain of proteins.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun an amino acid that is found in many proteins (especially collagen)

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[Short for pyrrolidine, one of its constituents : pyrrol(e) + –id(e) + –ine.]

from Wiktionary, Creative Commons Attribution/Share-Alike License

pyrrolidine

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Examples

  • She said it was already known the gene made a protein called proline rich transmembrane protein 2.

    NEWS.com.au | Top Stories 2012

  • Using advanced X-radiation techniques, University of Missouri researchers were able to visualize one of these terminals inside of an enzyme that degrades proline, which is an amino acid that has a central role in metabolism.

    EurekAlert! - Breaking News 2010

  • Unique PROSITE domains without INTERPRO annotations were ignored; these include low complexity regions such as proline-rich, serine-rich or glutamine-rich regions.

    PLoS ONE Alerts: New Articles 2009

  • A2 cows produce this protein with a proline at number 67, whereas A1 cows have a mutated proline amino acid, which converts it to histidine.

    Dr. Joseph Mercola: Why You Shouldn't Drink Pasteurized Milk 2010

  • The proline in A2 milk has a strong bond to another small protein called BCM 7, which helps keep it from being released.

    Dr. Joseph Mercola: Why You Shouldn't Drink Pasteurized Milk 2010

  • ALG fractions were identified as a sugar protein complex and the protein moiety of ALG contained high amounts of glutamic acid (or glutamine), threonine, asparagic acid (or asparagine) and proline.

    Allegic Reactions from Lactose in Dry Powder Asthma Inhalers Steve Carper 2008

  • A series of amino acids may be correlated to a series of codons but the logical linkage can be more like (a) create an acidic surface with the following amino acids (b) place these polar ones over there to enable an interface with another protein (c) disrupt an alpha helix with proline etc.

    Bits and Pieces of an RNA World 2007

  • But she soon learned that a local study of centenarians found that residents had high blood levels of proline and glycine, two compounds that assist in the regeneration of normal tissue and can be traced to the collagen and elastin in pork.

    The World's Diet Secrets Rebecca Ruiz 2009

  • "Dark chocolate reduced the urinary excretion of the stress hormone cortisol and catecholamines and partially normalized stress-related differences in energy metabolism (glycine, citrate, trans-aconitate, proline, β-alanine) and gut microbial activities (hippurate and p-cresol sulfate)."

    How dark chocolate helps ease emotional stress - latest scientific evidence 2009

  • In the event that you think you may have the flu, take the amino acids l-lysine, l-proline and l-glycine.

    Bird Flu Lakeside (A critical - literally - issue). 2005

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